17β-Acetoxyestra-4,9,11-trien-3-one CAS NO.10161-34-9

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Product Details

Keywords

Trenbolone acetate
stimulant steroid
Factory price and Top quality

Quick Details

ProName: 17β-Acetoxyestra-4,9,11-trien-3-one
CasNo: 10161-34-9
Molecular Formula: C20H24O3
Appearance: yellowish crystalline powder
Application: For research purposes only
DeliveryTime: One day
PackAge: apis or finished product
Port: Guangzhou;Shanghai;Shenzhen;HK
ProductionCapacity: 100 Kilogram/Day
Purity: 99.8%
Storage: cryo drying
Transportation: shipping by EMS,DHL,TNT,FEDEX,UPS or a...
LimitNum: 1 Gram
Moisture Content: 0%
Impurity: 0%

Superiority

Pharmacology

Pharmacodynamics

The administration of the trenbolone hormone promotes a direct anabolic effect on Androgen Receptor (AR) activity. AR activity facilitated by trenbolone contributes to an increase in IGF-1 and IGF-1R levels, which then enhances skeletal muscle protein accretion. Activation and proliferation of satellite cells then facilitate an increase in skeletal muscle growth.

Trenbolone acetate is a prodrug of trenbolone. Like other AAS, trenbolone is an agonist of the androgen receptor (AR) and hence has anabolic and androgenic activity as well as antigonadotropic activity.Trenbolone carries a rating for both anabolic potency and androgenic potency of 500, relative to a standard of nandrolone acetate (rating 100 for both). In addition to its anabolic and androgenic activity, trenbolone is an agonist of the progesterone receptor (PR), and in relation to this, has moderate to strong progestogenic activity.Conversely, trenbolone acetate is not a substrate for aromatase and hence lacks estrogenic activity. The compound also has weak glucocorticoid activity.

Similar to many other AAS, trenbolone acetate has the capability to produce insulin-like growth factor-1 (IGF-1).This naturally produced protein-based hormone affects every cell in the body of an organism and plays a large role in muscle recovery and rejuvenation. Trenbolone acetate also has the ability to increase the IGF-1 receptors present in an organism.Extreme muscle growth and cell splitting compared is facilitated through trenbolone acetate administration when compared to other AAS. The facilitation of IGF-1 plays a significant role in the functions and properties of the central nervous system, pulmonary system, muscle tissue, ligaments, cartilage, and tendons.IGF-1 is only promoted by a few AAS, with trenbolone acetate being one of the best promoters.

Trenbolone acetate also has the ability to increase red blood cell count. With a larger amount of red blood cells, blood oxygenation is enhanced. This allows for enhanced muscular endurance and therefore promotes a faster rate of recovery. Trenbolone acetate is capable of inhibiting glucocorticoids such as cortisol. The properties of glucocorticoid are the opposite of androgens as muscle tissue depletion and fat gain is promoted.Administration of trenbolone acetate aims at decreasing the production of glucocorticoid hormones. Trenbolone acetate’s contribution to feed efficiency, also known as nutrient efficiency is what makes it an attractive AAS used for agricultural purposes. Food is one of the most anabolic substances that any living organism can consume, and therefore with the administration of trenbolone acetate, every nutrient in the body becomes a lot more valuable.This facilitates an organism's body that is exposed to the AAS to make better use of the nutrients already consumed.The non-aromatizing nature of trenbolone acetate makes it a very appealing fat-burning agent. Its capability as a body-sculpting AAS is extreme.Many fitness models and bodybuilders use trenbolone acetate, particularly when preparing to compete in an upcoming bodybuilding competition.

Side effects

Trenbolone acetate, like any other AAS, has many side effects.The strong androgenic nature of trenbolone acetate facilitates its tendency to produce virilization and this is why it is not recommended for women for physique- or performance-enhancing purposes. The side effects of trenbolone acetate are similar to other AAS; however, the negative side effects that are specifically facilitated by trenbolone acetate are as follows.

Androgenic

Trenbolone acetate has androgenic activity. Specific to the androgenic properties of trenbolone, common side effects of the AAS use include oily skin, acne, seborrhea, increased facial/body hair growth, and accelerated scalp hair loss. These side effects strongly rely on an individual's genetics and may not always occur in every individual. Men susceptible to hair loss related illnesses, such as baldness have a higher chance of becoming permanently bald with the use of trenbolone acetate. In women, voice deepening, hirsutism, clitoral enlargement, and virilization in general may occur.

Hypogonadism

Trenbolone acetate contributes greatly to muscle mass and feed efficiency; however, administration of the AAS suppresses natural testosterone production; i.e., it causes hypogonadism.This is a common effect of all AAS; the only difference is the variation in how much they suppress in comparison to others.

Cardiovascular

Administration of any AAS can lead to cardiovascular issues. Trenbolone acetate can have a negative and strong impact on cholesterol through suppressing both high-density lipoprotein (HDL) cholesterol ("good" cholesterol) and increasing low-density lipoprotein (LDL) cholesterol ("bad" cholesterol).When compared to other oral AAS, trenbolone acetate has a stronger negative effect on cholesterol levels. This negative effect is much more severe with the use of injectable AAS, particularly trenbolone acetate.

"Tren cough"

The exact mechanisms underlying the cause of the tren cough is not known. However, trenbolone acetate's androgenic effect activates a variety of lipid-like active compounds which are called prostaglandins[citation needed]. Many of these prostaglandins are inflammatory and vasoconstrictive. Prostaglandins are signalled through two varying pathways cyclooxygenase (COX) (Also known as: prostaglandin-endoperoxide synthase) and lipoxygenases (LOX) (also known as: EC 1.13.11.34, EC 1.13.11.33, etc.). Vasoconstriction of the muscular wall of the bronchus in the lungs is what triggers this cough reaction. Trenbolone increases an inflammatory mediator peptide called bradykinin which facilitates the dilation of blood vessels. The bradykinin peptide is well known to promote a cough reaction associated with ACE inhibitor medications prescribed for hypertension.

Estrogenic and progestogenic

No form of trenbolone, including trenbolone acetate, is estrogenic. Excess fluid retention is not possible with the administration of this AAS as a result of its not being estrogenic as opposed to testosterone.However, due to trenbolone's potent progestogenic activity, gynecomastia, which is characterized by development and swelling of breast tissue,may still be possible. Stimulation of estrogenic mechanisms are enforced by progestogenic activity as trenbolone acetate and its compounds bind with high affinity to the progesterone receptor. It has been assumed that gynecomastia as a result of trenbolone use is due to a buildup of the hormone prolactin; however, a variety of studies conclude that it is the progestogenic activity of trenbolone promoting this and not prolactin. Trenbolone also has a negative impact on blood pressure, but it does not appear to negatively affect most healthy adult men in this way.

Details

FAQ

1. Can I get a free sample

Yes, but you have to pay the courier fee.

2. How to pay

We accept payments in the form of , MoneyGram, Bitcoin, etc.

3. What should I do if we don’t ship after payment

We are a formal company certified by LOOKCHEM Integrity, you can provide proof of payment to LOOKCHEM complaints.

4. How long after the payment can be shipped

We have stocked products that are shipped within 24 hours. If you need to customize the product, we will negotiate the delivery cycle.

5. How is the safety of transportation

We will choose the safest delivery method to ensure customs clearance and safety during transportation.

6. What kind of company is THETA BIO

In 2009, Dr Zhang Lin from Johns Hopkins University founded the theta Biological Laboratory. He is committed to the study of protein assimilation preparations.

In 2013,Dr Zhang Lin returned to China to work in MSD China, and continued to work on biopharmaceutical research and development.

In 2018,Dr Zhang Lin founded shaoyang Theta Biological Thechnology Co.,Ltd.

Business Scope:

Pharmaceutical intermediate

Biotechology development

Fine organic chemistry

Biopharmaceutical

History of the company

In 2009,Dr Zhang Lin from Johns Hopkins University founded the theta Biological Laboratory.He is committed to the study of protein assimilation preparations.